Epidemiology, pathogenesis and genetics of atrial fibrillation
نویسندگان
چکیده
منابع مشابه
Genetics of atrial fibrillation.
Recent studies of AF have identified mutations in a series of ion channels; however, these mutations appear to be relatively rare causes of AF. A genome-wide association study has identified novel variants on chromosome 4 associated with AF, although the mechanism of action for these variants remains unknown. Ultimately, a greater understanding of the genetics of AF should yield insights into n...
متن کامل[Epidemiology of atrial fibrillation].
UNLABELLED FREQUENCY: Atrial fibrillation is the most frequent sustained arrhythmia, especially in the elderly. The incidence accounts for 2% past the age of 40 years, 6% over 70, an approximately 15% over 90 years old. PATHOGENESIS Primary cause in "idiopathic" atrial fibrillation is differentiated from secondary causes of cardiac and non-cardiac origin. Important predictive cardiovascular d...
متن کاملMolecular genetics of atrial fibrillation.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. There is genetic predisposition for the development of AF. Recently, by linkage analysis, several loci have been mapped for monogenetic AF, including 11p15.5, 21q22, 17q, 7q35-36, 5p13, 6q14-16, and 10q22. Some of these loci encode for subunits of potassium channels (KCNQ1, KCNE2, KCNJ2, and KCNH2 genes), and the remainin...
متن کاملMolecular Genetics and Epidemiology of Vitiligo
Background: Vitiligo is an acquired, idiopathic, and common depigmentation disorder of the skin that affects people of all ages and both sexes equally in the worldwide. Although etiology of the disease is unknown, there are theories such as environment and genetic factors. Methods: In this article, we collected and summarized the appropriate manuscripts regarding the epidemiology and gene...
متن کامل[Atrial fibrillation. I. Etiology and pathogenesis].
Etiology and pathomechanisms of atrial fibrillation and atrial flutter are complicated and the knowledge about them still remains incomplete. This may be the reason why currently applied methods of prevention as well as treatment remain unsatisfied. A number of clinical situations were identified that may conduce to occurrence of atrial fibrillation and atrial flutter and also lead to chronic f...
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ژورنال
عنوان ژورنال: Medwave
سال: 2012
ISSN: 0717-6384
DOI: 10.5867/medwave.2012.03.5337